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The evidenced marked congestion within the myocardium and large coronary branches included the occlusion of the superior mesenteric vein [24], the occlusion of the superior mesenteric artery [19], the simultaneous occlusion of both the superior mesenteric artery and the superior mesenteric vein [29], and centrally, the occlusion of the superior sagittal sinus [27]

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These results suggest that depletion of GSH is associated with a significant induction in the grx and rnr expression, probably in response to the oxidative damage observed in nDNA of the mutant parasites